产品货号：
Z13900
中文名称：
DAXX抗体
英文名称：
Anti-DAXX Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DAXX Antibody |
| 指标别名 | BING2;DAP6;DAXX;EAP1;ETS1 associated protein 1;hDaxx |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | DAXX |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human Daxx(325-341aa QERRHLDLIYNFGCHLT),identical to the related mouse and rat sequences. |
| 实际分子量 | 115KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DAXX(death-domain associated protein) also known as DAP6(Death-associated protein 6) or BING2,was first discovered through its cytoplasmic interaction with the classical death receptor Fas.Human DAXX encodes a 740-amino acid polypeptide containing a nuclear localization signal.Functional analyses by Yang et al.(1997) demonstrated that Daxx binds to the Fas death domain and enhances Fas-mediated apoptosis.The authors suggested that DAXX and FADD define 2 distinct apoptotic pathways downstream of Fas.The DAXX gene is mapped to human chromosome 6p21.3 by somatic cell hybrid panels and fluorescence in situ hybridization,a region containing the HLA and putative autoimmune disease genes.MSP58 overexpression relieved DAXX-mediated transcriptional repression.Immunoprecipitation and Western blot analysis with DAXX mutants showed that the N terminus of DAXX interacts with the C terminus of DMAP.Transient expression of DAXX or DMAP1 caused repression of glucocorticoid receptor-mediated transcription. |
| Uniprot ID | Q9UER7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | death-domain associated protein |
| 蛋白名全称 | Death domain-associated protein 6 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
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